TGFB1 and Posterior Leukoencephalopathy Syndrome: Ciampa et al. demonstrated that differentially expressed proteins in the CSF of PE mothers converge to four signaling molecules, including TGF-β, vascular endothelial growth factor A, angiotensinogen, and IL-6, suggesting that neurological maternal complications of PE, such as eclampsia and posterior reversible encephalopathy syndrome, are associated with vascular remodeling, inflammation, neuronal growth, signaling, and electrophysiology (33).