BRCA1 and invasive carcinoma: Different series about pathologic findings at RRSO have shown that, in women with a pathogenic BRCA1/2 variant, 4.5% to 9% were found to have occult gynecologic neoplasia, including invasive carcinomas and intraepithelial lesions, through thorough pathologic examinations of their ovaries and fallopian tubes (39).