A study (58) from France included 32 patients with pancreatic adenocarcinoma and showed that a high level of sPD-L1 (>0.36 ng/ml) was related with worse OS (median OS, 9.41 months in high level of sPD-L1 vs. 19.87 months in low level of sPD-L1). The gene discussed is SPDL1; the disease is pancreatic adenocarcinoma.