1. sPD-L1 level was related with DFS (HR, 5.42; p<0.001) and OS (HR, 9.67; p<0.001).2. High sPD-L1 predict high level of recurrence (p<0.01); there was no relation to complete treatment3. A positive correlation between sPD-L1 and PD-L1 expression in cancer cells was found (p=0.01). Here, CD274 is linked to cancer.