IL6 and Sepsis: (Angele et al., 2014) Moreover, proinflammatory cytokines possibly contributing to the dysregulated host response, e.g. IL-6 and procalcitonin, have been found to be elevated in male patients compared to female patients with severe injury, and the incidence of post-traumatic sepsis is higher in men even when the extent of the predisposing injury is similar.