Through Pan-Cancer Analysis of Whole Genomes (PCAWG) analysis of m6A modification of telomerase components, it was found that in most cancers, the expression level of telomerase components was positively correlated with methylase METTL3, negatively correlated with methylase METTL14, negatively correlated with demethylase FTO, negatively correlated with reading proteins YTHDC1, YTHDC2, YTHDF3 and FMR1, and positively correlated with reading proteins HNRNPC, HNRNP2B1, YTHDF1 and RBMX (Wang et al., 2023). The gene discussed is MBD2; the disease is cancer.