Comparison of the patient’s clinicopathological characteristics with the two groups, significant correlation was found between γ-OHPdG levels and presurgical AFP levels (Table 1), but other baseline variables including age, sex, HbsAg, HBV DNA load, ALT, AST, TBIL, prothrombin time, alcoholism, long-term smoking, HCC family history, surgical procedures, nodule numbers, tumor capsule, surgical margin, neoplastic necrosis, satellite nodules and background liver function, were not associated. The gene discussed is AFP; the disease is alcohol drinking.