These cells could be clustered into three cell types with different gene signatures (Figure 5A and Supporting Information Figure S11D): hepatic cells (HPCs) were characterized by expression of KRT8, KRT18, ADH1A, ADH4 and AHSG; tumour‐associated macrophages (TAMs), characterized by expression of CD14, CD163, CSF1R, CST3, FCGR2A and LYZ; and tumour‐associated endothelial cells (TECs), characterized by expression of CDH5, ENG, PECAM1 and VWF (Figure 5B). This evidence concerns the gene CST3 and neoplasm.