Further blood analysis showed low cortisol (< 0.50 nmoL/L), normal renin (44.9 mU/L, normal values 5.5–80 mU/L), low aldosterone levels (26.9 pmoL/L, normal values 138–831 pmol/L) with high adrenocorticotropic hormone (ACTH > 278 pmoL/L), confirming the suspect of primary adrenal insufficiency. This evidence concerns the gene POMC and primary adrenal insufficiency.