APOE and Alzheimer disease: The addition of either PRS to a model including age, sex, and APOE did not improve AD or ACD prediction accuracy (c-statistic, 95%CI: AD: age + sex + APOE + Kunkle PRS: 0.787, 0.754–0.820; age + sex + APOE + Bellenguez PRS: 0.788, 0.755–0.821; ACD: age + sex + APOE + Kunkle PRS: 0.768, 0.747–0.789; age + sex + APOE + Bellenguez PRS: 0.768, 0.747–0.789).