A well-represented protein was the T-cell immunomodulatory protein (W6V8B8 ortholog of Em-TIP), which has previously been characterized as an E/S product in E. multilocularis primary cell cultures involved in metacestode development and in the promotion of IFN-γ release by murine Th1 cells during the early stages of infection [72]. This evidence concerns the gene IFNG and infection.