WDR4 and cancer: We also found elevated expression of WDR4 (Fig. 1C), the regulatory subunit of the m7G RNA methyltransferase complex [30, 31], which is also overexpressed in other cancers [22, 28, 29, 38, 39]; however, we did not find WDR4 overexpression to be a risk factor for poor prognosis (Fig. 1D; Supplementary Fig. S1C).