FGF2 and Alzheimer disease: Nevertheless, using the IVW method, genetically predicted AD demonstrated a nominally causal effect on basic fibroblast growth factor (bFGF) (β, 0.05; 95% CI 0.021–0.079; p-value = 0.017), in line with findings using the weighted median method and MR-Egger method; and genetically predicted AD demonstrated a nominally causal effect on IL-12 (β = 0.040; 95% CI 0.020 to 0.060; p-value = 0.046).