We previously observed that two dimeric PCA isolated from persimmon fruits, composed of epicatechin-3-gallate (ECG) and epigallocatechin-3-gallate (EGCG) subunits linked by 4β→8 and 2β→O→7 bonds (Fig. 1), inhibit in vitro CRC cell growth and promote apoptosis by regulating the EGFR pathway [39]. Here, EGFR is linked to colorectal carcinoma.