It has been demonstrated that m6A regulates the metabolism, maturation, degradation, nuclear output, and mRNA translation, which further regulates various physiological and pathological functions.[8, 15] YTHDF2, an important reader of m6A modification, can selectively bind m6A ‐methylated mRNA to control RNA decay in a methylation‐dependent manner.[7a] The expression levels of YTHDF2 differ among malignant tumors, and its exact function is still debatable. Here, YTHDF2 is linked to cancer.