The effects of cuproptosis on TIME revealed a higher expression of chemokines in Cluster 1 in TCGA, meta, LGG, and glioblastoma cohorts, such as CXCL12, CXCL10, CCR5, CCR10, CCL5, and CCR2 (Figure 2A), attracting immunosuppressive cells, such as Tregs, macrophages, myeloid‐derived suppressor cells (MDSCs), and monocytes, vital in immune escape. The gene discussed is CCR5; the disease is glioblastoma.