Cytokines play a fundamental role in COVID-19 since the severity of the disease has been associated with an exuberant production of proinflammatory cytokines, such as IL-1, IL-2, IL-6, IL-10, IL-12, IFN-γ, TNF-α, and, consequently, an excessive activation of the immune system, which may cause tissue injury, mainly on the lungs [25]. The gene discussed is IL1B; the disease is COVID-19.