HLA-DOA and focal epithelial hyperplasia: The incidence of HPV types associated with Heck’s disease was much higher among Indigenous Australian adults (16.1%) than non-Indigenous Australian young adults (3.2% HPV 32 and 0% HPV 13) [39], which may be associated with Indigenous genetic susceptibility, such as the human lymphocytic antigen (HLA)-DR4(DRB1*0404) allele occurring frequently in Indigenous populations of the Americas [40].