Hormone receptor status (hazard ratios (HRs) = 0.15, 95% [confidence intervals (CI)] 0.03–0.71), tumor size (HRs = 3.36, 95% [CI] 1.26–8.97), lymph node involvement (HRs = 10.29, 95% [CI] 1.31–80.73), molecular subtype (HRs = 1.99, 95% [CI] 1.01–3.92), tumor stage (HRs = 4.73, 95% [CI] 1.38–16.19) and HIV status (HRs = 8.26, 95% [CI] 1.64–41.66) were found in association with breast cancer disease progression by a univariate COX analysis. The gene discussed is NR4A1; the disease is breast carcinoma.