In malignant cells with an activated Ras pathway, it has been suggested that either directly through Ras mutation or indirectly via upregulation of epidermal growth factor receptor (EGFR) signaling or of other signaling components [5,8,9,10,11], this cellular antiviral response mechanism may be perturbed, viral replication enhanced, and subsequent lysis of the host cancer cell facilitated. Here, EGFR is linked to cancer.