RAP1B and viral infectious disease: Encouragingly, transient expression of the full prenylation mutant (Rap1b-CAAX) accelerated virus infection in a highly significant dose-dependent manner, even higher by about 33% at a 0.5 μg transfection amount than the Rap1b (AA) mutant with a 3 μg transfection amount, which broke the limit of wild-type Rap1b’s promoting effect on virus infection at a high transfection dose (Figure 2E).