Furthermore, these authors found that IGF2BP1 can also bind to the HCV 3′UTR in vitro and that IGF2BP1 knockdown in HCC-derived Huh-7 cells leads to strongly decreased HCV IRES-mediated translation rates that were even further reduced in the absence of the HCV 3′UTR. Here, IGF2BP1 is linked to hepatocellular carcinoma.