ANTXR2 and infection: The heterosubtypic iPR8/H1N1-iSH/H7N9 prime-boost group showed survival protection by displaying weight loss (~18%) and 100% survival rate against HK/H9N2 virus challenge as compared to the homologous iPR8/H1N1-iPR8/H1N1 and naïve infection groups that displayed weight losses of over 25% and 0% survival rates (Figure 8A,B).