Intraperitoneal injections of C. crescentus were administered before and after subcutaneous tumor implantation (EL4 or B16 cells) in C57BL/6 mice, Jα18−/− mice (lacking type I NKT cells), and CD1d−/− mice (lacking CD1d-restricted NKT cells) [383]. Here, CD1D is linked to neoplasm.