The data show that overexpression of CK2 and PIM-1 kinases is a poor predictor in many cancers, such as prostate cancer and breast cancer, among others [17,18,19], and the reduction in CK2 and PIM-1 activity by chemical or molecular methods induces apoptosis in tumor cells [20,21,22]. The gene discussed is PIM1; the disease is breast carcinoma.