VEGFA and neoplasm: For example, vascular endothelial growth factor (VEGF) siRNAs and B-cell lymphoma/leukemia-2 (Bcl-2) siRNAs, which were used to functionalize gold nanoparticles entrapped in dendrimers for gene silencing applications on U87-MG cells in vitro and the xenografted tumor model in vivo [57].