SQLE and fungal infectious disease: Unlike bacterial pathogens, fungal infections are mainly treated with five classes of drugs, namely, azoles (for systemic and superficial fungal infections) [11,12], polyenes (for severe systemic fungal infections) [13], echinocandins (for intractable fungal infections) [14,15], allylamines (which inhibit squalene epoxidase activity and disrupt the ergosterol synthesis pathway) [16], and antimetabolites (which inhibit fungal RNA and DNA synthesis) [17].