For example, miRNA-dependent APP (amyloid precursor protein) neurotoxicity is a splicing-dependent process in AD pathology and involves miR-101, miR-20a, miR-17-5p, miR-106b, miR-106a, miR-520c, miR-16, miR-124, miR-147, miR-153, miR-644, and miR-323. Here, APP is linked to Alzheimer disease.