FOLH1 and neoplasm: PET imaging showed optimal tumour uptake at 4 h p.i. and evaluation of therapeutic potential showed that a single dose of 150 MBq [64Cu]Cu-DOTAH2-PSMA or 120 MBq [177Lu]Lu-PSMA-617 significantly increased the median survival of mice compared with control mice in a similar manner and without inducing significant toxicity.