Reduction in tumor weight and induction of apoptosis (↑ cytochrome c ↓ Bcl-2, ↑ Bax and pJNK, ↑ caspase 3), cell cycle arrest (↓ CDK2 and cyclin A and ↑ p21) and autophagy (↑ LC3-II). Here, CASP3 is linked to neoplasm.