Nguyen et al. [31] measured the cardiac and plasma galectin-3 in several models of heart diseases in mice and demonstrated that both plasma and heart galectin-3 levels were increased in mice with fibrotic cardiomyopathy, ischemia-reperfusion-induced heart disease, and overactivation of β-adrenergic receptor-induced cardiomyopathy. The gene discussed is LGALS3; the disease is cardiomyopathy.