Figure 8 shows that incubation of cancer cell lines with 2′-OH-Torosaol I significantly increased activated caspase-3 in all three cell lines evaluated when compared with the control group. The greatest involvement occurred in K562 cells (Figure 8C,D), where the increase in activated caspase-3 was approximately 3.5-fold higher than in the control group. Here, CASP3 is linked to cancer.