The anti-oxidant effects induced by OleA and HT are associated with a reduction in the nuclear translocation of NF-kB, pro-inflammatory agents, including COX-2, iNOS, NO and IL-6, IL-8, IP10 and RANTES, whose increased levels are correlated with an increased risk of dementia and neurological disorders [42,43,44]. This evidence concerns the gene PTGS2 and nervous system disorder.