G6PD and hyperinsulinemic hypoglycemia, familial, 4: In this context, considering the diverse functional properties of CYPs, and the scarcity of studies about PQ metabolism associated with G6PD deficiency, this study aimed to evaluate the association of CYP2C19, CYP2D6 and CYP3A4 genetic variants with primaquine hemolysis in G6PD-deficient patients.