Pharmacological therapy is the first line of treatment, however, it can cause long-term complications such as dyskinesias The pharmacological alternatives used for the treatment of PD may include levodopa, monoamine oxidase-B (MAO-B) inhibitors, mainly rasagiline and selegiline, and catechol -Omethyltransferase (COMT), anticholinergics and dopamine agonists [11,12]. This evidence concerns the gene MAOB and Parkinson disease.