INS and bronchiolitis obliterans syndrome: Pre-lunch insulin IAUC and TAUC were significantly lower in BO versus BC (p < 0.0005; d = 1.23 to 1.25), whereas post-lunch insulin IAUC and TAUC were significantly higher in BO versus BC (p ≤ 0.0005; d = 1.58 to 1.91); these effects were all large.