TNFα expression was markedly increased in the endothelium (CD vs. AD: 0.33 ± 0.06 PI, p < 0.0001) (Figure 6A,F,H), media (CD vs. AD: 0.39 ± 0.08 PI, p < 0.0001) (Figure 7A,F,I) and adventitia (CD vs. AD: 0.21 ± 3.58 × 10−3 PI, p < 0.0001) (Figure 7A,F,J) of AA rings from AD rabbits when compared to CD rabbits. The gene discussed is TNF; the disease is Alzheimer disease.