In this regard, a recent review highlighted that some bacterial strains, including those stimulated via α-LA (Lactobacillus acidophilus, Bifidobacterium short, Bifidobacterium longum, and Bifidobacterium infantis), are associated with significant improvements in glycated hemoglobin and HOMA index in patients with T2DM, suggesting the positive effects of α-LA in restoring altered metabolic parameters [19]. The gene discussed is SSB; the disease is type 2 diabetes mellitus.