To further elucidate the ability of ATLIII to regulate metabolites, the differential metabolites and metabolic pathways associated with liver fibrosis were identified based on VIP > 1 in the orthogonal projection to latent structures square discriminate analysis (OPLS-DA) model combined with p < 0.05 in the Student’s t-test (Figure 6F,I). This evidence concerns the gene VIP and Hepatic fibrosis.