In RA synovium-derived fibroblasts, EGCG at 10-20 μM inhibited the production of IL1β-induced epithelial neutrophil activating peptide-78, RANTES, and CXCL1, but monocyte chemotactic protein 1 (MCP1) production was inhibited at much higher concentrations [62]. Here, IL1B is linked to rheumatoid arthritis.