In multivariate COX regression analysis, even adjusted by these six clinical factors (age > 65, diagnosis of DCM-HF, LVEF < 35%, left atrial diameter > 55 mm, serum creatinine > 2 mg/dL and NT-pro-BNP > 4000 pg/mL) together with C18:2 > 420 nmol/L, C4DC > 60 nmol/L and isoC5 < 100 nmol/L also increase the incidence of HF rehospitalization independently, Table 5. Here, NPPB is linked to familial dilated cardiomyopathy.