Interestingly, our study also revealed hub genes (MEG3, MIAT, IRF1, ADAMTS9-AS2, TP63, NOD2, NOD1, NLRP3, MAGI2-AS3, and PVT1, respectively) within the pyroptosis-related ceRNA network, some of which have been well-studied in the field of cancer biology. Here, MEG3 is linked to cancer.