AKT1 and cancer: GL has been shown to regulate cancer cell death, oxidative stress, and inflammation by modulating various signaling pathways, such as MAPK, phosphatase and tensin homolog/phosphatidylinositol 3-kinase/protein kinase B pathway (PTEN/PI-3K/PKB), and the mammalian target of rapamycin/signal transducer and activator of transcription 3 (mTOR/STA3) axis in several cancer cell types [52].