We screened the risk models of 12 m6A-related genes (RBM15, YTHDC1, ZC3H13, YTHDF1, METTL3, ALKBH5, WTAP, METTL14, FTO, YTHDC2, YTHDF2, and HNRNPC) to predict the OS in patients with COAD. This evidence concerns the gene YTHDC1 and colon adenocarcinoma.