Further, the NGF/NTRK1 (or TrkA) signaling axis modulates the survival, growth, and prevention of apoptosis through the PLCγ1, the PI3K-Akt, and the Ras/Raf/MEK/ERK 1/2 pathways, which are implicated in BC carcinogenesis [64,65]. The gene discussed is AKT1; the disease is breast cancer.