Additionally, proteins of AKT are also involved in the mammalian target of the rapamycin (mTOR) signaling pathway which regulates the eukaryotic translation initiation factor 4F (eIF4E) complex assembly, where this pathway is involved in the stimulation of extracellular signals from cytokines and growth factors which are dysregulated in numerous cancers [12]. Here, AKT1 is linked to cancer.