PIK3CD and chronic obstructive pulmonary disease: A 49-year-old male patient affected by Activated PI3K delta syndrome (APDS1 with mutation in PIK3CD c.1573G > A; p. Glu525lys) with a history of bronchiectasis, chronic obstructive pulmonary disease (COPD), and EBV-related large B cell NHL, treated with R-CHOP regimen (Rituximab, Cyclophosphamide, Hydroxydanorubicin, Vincristine, Prednisone) and substernal radiotherapy.