The first group (Figure 4A) consists of 15 proteins (ADCY3, CDC25C, CENPO, DNAJC27, EFR3B, FTO, GPRC5B, IQCK, KIAA0368, KIF20A, etc.)associated with BMI-related phenotypes (fat body mass, obesity, height). Here, ADCY3 is linked to obesity due to melanocortin 4 receptor deficiency.