IL1B and arthritic joint disease: Significant reduction of paw edema and arthritis scores. Improvement of the spleen and thymus indexesReduction of TNF-α, IL-1β, IL-6, IFN-γ levels in CIA ratsIncrease in superoxide dismutase activity; reduction of malondialdehyde and superoxide anions levels and NADPH oxidase activityPotential therapeutic effects on RA may be ascribed to downregulation of inflammatory cytokine levels and attenuation of oxidative stress