Suppression of the migratory capacity of RA FLSsDownregulation of the mRNA expression of IL-1β, IL-6, IL-8 and IL-17A in TNF-α-induced RA FLSsDecrease in TNF-α-induced activation of NF-κB signal pathway (phosphorylated NF-κB, IκBα and IKK) and the NF-κB nuclear accumulationInhibitory effect of NF-κB PDTC on the formation of actin stress fibers and actin cytoskeleton score of RA FLSsAttenuation of synovitis, synovial hyperplasia and invasion into calcified cartilage and bone in CIA mice. This evidence concerns the gene NFKB1 and rheumatoid arthritis.