GRIN1 and epilepsy: Developmental regression, autism, and epilepsy can also be seen in disorders of ion channels (i.e., Dravet syndrome), impairments of receptor expression (i.e., GRIN1), transcription factors (i.e., MEF2C), axonal guidance (i.e., NTNG1), and ubiquination (i.e., RHOBTB2) [48].