GRIN1 and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: Developmental regression, autism, and epilepsy can also be seen in disorders of ion channels (i.e., Dravet syndrome), impairments of receptor expression (i.e., GRIN1), transcription factors (i.e., MEF2C), axonal guidance (i.e., NTNG1), and ubiquination (i.e., RHOBTB2) [48].