Abbreviations: d: day, w: week, y: years, T1D: type 1 diabetes, MDI: multiple daily injections, CSII: continuous subcutaneous insulin infusion, CGM: continuous glucose monitoring, SAP: sensor-augmented pump, LGS: low glucose suspend, PLGM: predictive low-glucose monitoring, AID: automated insulin delivery, AP: artificial pancreas, BP: bionic pancreas, CIQ: Control IQ, DTQ: diabetes technology questionnaire, DTSQ: diabetes treatment satisfaction questionnaire; IU: intention to use, PU: perceived usefulness, PE: perceived ease of use, T: trust, RCT: randomized controlled trial. This evidence concerns the gene INS and diabetes mellitus.